German E. coli Found to be MDRO


Most bacteria readily develop multi-drug resistance. (Credit: Chrisharvey/Dreamstime)

New research has recently confirmed that the E. coli from the German outbreak had multiple-drug resistance. This is called a multi-drug resistant organism. The current conspiracy theory circulating that this means that the E. coli organism had to have been genetically modified by corporate or terrorist forces is unfounded, according to multiple studies.

There are many species of microorganisms that have been shown to become multi-drug resistant. Microorganisms become multiple-drug resistant because they exchange DNA packets called plasmids. These plasmids give them the ability to develop tools to evade a specific antibiotic or group of antibiotics. Because microorganisms of the same species will travel, and because the readily exchange these plasmids, a particular microorganism can easily become resistant to many types of antibiotics. Researchers have seen MDROs have resistance to more than ten different antibiotics or antibiotic families.

Furthermore, many different microorganisms have developed multi-drug antibiotic resistance. Some of the more dangerous MDROs include species of Enterococcus, Staphylococcus, Salmonella, Campylobacter, and others – in addition to Escherichia coli. Superbugs such as MRSA are only the tip of the bacterial iceberg, as it were.

Illustrating this, a study performed by researchers from India’s Department of Veterinary Microbiology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University overseen by professor Dr. Ashish Roy, measured antibiotic resistance among 41 different Shiga toxin-producing Escherichia coli strains. They found that every strain was resistant to at least 3 antibiotics, and many strains were resistant to many more, up to twelve.  Among the antibiotics they had resistance to was:

  • kanamycin
  • cephalexin
  • cephaloridine
  • enrofloxacin
  • amikacin
  • ampicillin
  • tetracycline
  • ceftiofur
  • ciprofloxacin
  • colistin
  • co-trimoxazole.

The EHEC O104 strain – the main strain said to be responsible for the outbreak – was one of the strains of proven MRDOs tested.  The study was  published in the Journal Zoonoses Public Health, and has been cited by a number of respected researchers.

In another study, this one by researchers from Japan’s Osaka City University Medical School, and published in the Journal, Epidemiology and Infection, also found many multi-drug resistant strains of E. coli.

This study analyzed 455 Escherichia coli strains isolated from pigs. They found that many of the strains were resistant to chloramphenicol, ampicillin, kanamycin, trimethoprim-sulphamethoxazole, ofloxacin and gentamicin among others.

They found that many of the E. coli strains had multi-drug resistance to up to seven antimicrobial drugs at once.


Arya G, Roy A, Choudhary V, Yadav MM, Joshi CG. Serogroups, atypical biochemical characters, colicinogeny and antibiotic resistance pattern of Shiga
toxin-producing Escherichia coli isolated from diarrhoeic calves in Gujarat, India. Zoonoses Public Health. 2008;55(2):89-98.

Kumai Y, Suzuki Y, Tanaka Y, Shima K, Bhadra RK, Yamasaki S, Kuroda K, Endo G.Characterization of multidrug-resistance phenotypes and genotypes of Escherichia
coli strains isolated from swine from an abattoir in Osaka, Japan. Epidemiol Infect. 2005 Feb;133(1):59-70.

Probiotics: Protection Against Infection


Case Adams is a California Naturopath with a PhD in Natural Health Sciences, and Board Certified Alternative Medicine Practitioner. He has authored 26 books on natural healing strategies. “My journey into writing about alternative medicine began about 9:30 one evening after I finished with a patient at the clinic I practiced at over a decade ago. I had just spent the last two hours explaining how diet, sleep and other lifestyle choices create health problems and how changes in these, along with certain herbal medicines and other natural strategies can radically yet safely turn ones health around. As I drove home that night, I realized I needed to get this knowledge out to more people. So I began writing about health with a mission to reach those who desperately need this information. The strategies in my books and articles are backed by scientific evidence along with wisdom handed down through traditional medicines for thousands of years.” Case connects with the elements by surfing, hiking and being a beach bum.

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